Cyclofertilography is the method developed and protected by VivoSensMedical for the objective assessment of female cycle health and fertility. It is based on continuous measurement of core body temperature using a vaginal biosensor (OvulaRing) and digital analysis of the data with medical algorithms.

What Is Cyclofertilography?

In cyclofertilography, a woman’s core body temperature is recorded continuously throughout the entire cycle – day and night, over many cycles. The data are transmitted and analyzed automatically. The result is a cyclofertilogram (CFG) and a CFG score that represent, among others, the following parameters:

• Length of the cycle and the individual cycle phases
• Timing of ovulation and the fertile window
• Duration of the hyperthermic (luteal) phase
• Potential cycle disorders or anovulatory cycles

This enables cyclofertilography to provide objective, data-based cycle and fertility diagnostics that go far beyond classical basal temperature or single-point measurements.

Medical Concept

Cyclofertilography combines continuous temperature measurements with intelligent pattern recognition:

• Continuous, high-resolution measurement of core body temperature (288 data points per day)
• Vaginal ring-shaped biosensor, worn like a pessary and hardly noticeable in everyday life
• Web-based software and app for secure data transmission and graphical visualization
• Medical algorithms for detecting individual cycle and fertility patterns

This allows cycle phases and ovulation to be determined precisely, luteal phases to be assessed, and hormonal irregularities such as luteal phase insufficiency or PCOS to be identified more accurately – including in the context of fertility and hormone therapies.

Benefits for Healthcare Professionals

For gynecologists, endocrinologists, fertility centers and other medical professionals, cyclofertilography offers clear added value:

• Objective cycle diagnostics in cases of infertility and unclear cycle disorders
• More precise planning of hormonal diagnostics (e.g. progesterone measurements) and therapies
• Therapy monitoring for hormone treatments, stimulation cycles and IVF protocols
• Telemedical care through digital data transmission and analysis outside the practice
• New data quality for research in reproductive medicine, women’s health and chronobiology

Cyclofertilography thus closes an important gap between classical cycle observation and complex hormonal or imaging diagnostics.

Benefits for Partners & Investors

Cyclofertilography is more than a method – it is the basis for scalable, digital business models in the field of femtech and precision medicine:

• CE-certified class IIa medical device with patented sensor technology and algorithms
• Validated technology with thousands of recorded cycles and multiple clinical studies
• Platform-ready system for B2B and B2B2C collaborations (clinics, practices, digital health providers)
• Transferable principle to additional indication areas such as autoimmune diseases and chronobiology
• Attractive positioning in the growing market for data-driven women’s health and reproductive medicine solutions

Together with strong partners, new care models, reimbursement pathways and digital services for patients can be developed on the basis of cyclofertilography.

Collaboration & Contact

Are you a healthcare professional, clinic, research partner or investor and would like to integrate cyclofertilography into your work or portfolio?
We look forward to exchanging ideas and working together on joint projects – feel free to get in touch with us.